According to the Mayo Clinic, however, Karo syrup is not actually effective in curing constipation.
Often, just giving the baby as much as two ounces of water once or twice a day is all that is needed to soften the stools. For infants who are already on solid foods (five months or older), pureed prunes are another good way to treat constipation.
There are a number of remedies floating around that that do or don't work, and it's hard to know which is which. We at FamilyEducation put together a quick roundup of five remedies in this video.