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Meaning and Origin of: Mayo

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First name origins & meanings:

  • Irish : Nature-loving; yew tree

First name variations

Last name origin & meaning:

  • English and Irish : variant of Mayhew.
  • Variant of French Mailhot.
  • A William Mayo born in Wiltshire, England, c. 1684 was a surveyor who settled in VA about 1623 and helped survey the VA-NC boundary and found Richmond and Petersburg, VA. [newpara]The Mayo Clinic in Rochester, MN, was founded by William Worrall Mayo (1819–1911), who immigrated to the U.S. from England, in 1845, and his sons, all gifted and innovative physicians and surgeons.